50 years of life-changing therapies

On November 12 1975, the first allogeneic bone marrow transplantation in Sweden was performed at Huddinge Hospital, here in Flemingsberg. From nuclear catastrophe the foundations of bone marrow transplantation had emerged, and with it, the birth of modern stem cell therapy — the same principles that today underpin cell and gene therapies and CAR-T treatments.

On November 28th the 50 years passed was celebrated – and 50 years of CAST (Cell Therapy and Allogeneic Stem Cell Transplantation). The unit that, under the leadership of Professors Gösta Gahrton and Carl-Gustav Groth, carried out the historic transplantation, and has since tirelessly worked to develop new therapies, and save lives.

In honor of that a scientific symposium was held in Birkeaulan at Karolinska University Hospital. Led by Professors Stephan Mielke and Mattias Carlsten, leading experts from Sweden and abroad gathered to highlight how innovation in cell and gene therapy can be translated from research to patients. Through lectures and panel discussions, both CAST’s mission and development, as well as global perspectives on advanced treatments, where showcased. The program also provided insight into ongoing research and future possibilities.

The symposium and celebration not only highlighted ongoing research and future opportunities, but also showed how CAST’s five decades of innovation have contributed to shaping today’s advanced treatments and a unique research environment here in Flemingsberg. A reflection of the enormous expertise, courage, and forward-looking spirit among the dedicated staff who work every day to change the lives of thousands of patients. Or as Christophe Pedroletti, CEO of Karolinska Universitetssjukhuset expressed it so well:

“A long carried and clear vision – to one day cure and relieve what no one else can cure or relieve today. These are big words, but here at CAST, they are not abstract. They take shape in everyday work, in the corridors, in the treatment rooms, in the research labs, and in conversations with families. And we never do this alone – Karolinska University Hospital and Karolinska Institutet are two parts of the same whole. A partnership where care, research and education move in step. Without that close collaboration we would not be standing here today, celebrating half a century of progress.”

Taking the leap as a solo developer in Sweden’s growing game industry

Jacques Diringer left a secure job at the game giant King to follow his dream of creating his own game from scratch. In a Stockholm where the gaming industry is growing rapidly and new companies are launched every year, he now embarks on a more uncertain but creative journey. The path has been both challenging and inspiring, shaped by a vibrant gaming community, new collaborations, and the courage to trade stability for freedom.

Steps shaping innovation and growth – Natasha Bank sums up the first year of Life Science Cluster Flemingsberg

A future life science cluster isn’t built in a year – but with a solid foundation and the courage to act, important steps can be taken along the way. In February 2025, we launched Life Science Cluster Flemingsberg: a multifaceted project with powerful, interconnected ambitions – to enable Flemingsberg’s life science cluster to reach its full potential by collaboration and creating the right conditions for the establishment and growth of those who drive innovation – small and medium-sized enterprises – and, in doing so, contribute to the Stockholm region’s leading position within the sector.

Johnny Högberg Summarizes 2025 – A Year of Growth and Collaboration in Flemingsberg

We are most effective and make the greatest impact when we engage our founders and leverage their size, organizations, and influence, and we still strongly believe in this. At the same time, the fact that we have grown as an organization has also made a difference. Today, we are exactly the kind of “two-pizza team” that Amazon founder Jeff Bezos highlights as the most effective. Among other things, we are now running two cluster initiatives and creating a level of engagement, buzz, and content that is noticeable in Flemingsberg and is actually helping to change the area.

Go to Top