50 years of life-changing therapies

On November 12 1975, the first allogeneic stem cell transplantation in Sweden was performed at Huddinge Hospital, here in Flemingsberg. From nuclear catastrophe the foundations of bone marrow transplantation had emerged, and with it, the birth of modern stem cell therapy — the same principles that today underpin cell and gene therapies and CAR-T treatments.

On November 28th the 50 years passed was celebrated – and 50 years of CAST (Cell Therapy and Allogeneic Stem Cell Transplantation). The unit that, under the leadership of Professors Gösta Gahrton and Carl-Gustav Groth, carried out the historic transplantation, and has since tirelessly worked to develop new therapies, and save lives.

In honor of that a scientific symposium was held in Birkeaulan at Karolinska University Hospital. Led by Professors Stephan Mielke and Mattias Carlsten, leading experts from Sweden and abroad gathered to highlight how innovation in cell and gene therapy can be translated from research to patients. Through lectures and panel discussions, both CAST’s mission and development, as well as global perspectives on advanced treatments, where showcased. The program also provided insight into ongoing research and future possibilities.

The symposium and celebration not only highlighted ongoing research and future opportunities, but also showed how CAST’s five decades of innovation have contributed to shaping today’s advanced treatments and a unique research environment here in Flemingsberg. A reflection of the enormous expertise, courage, and forward-looking spirit among the dedicated staff who work every day to change the lives of thousands of patients. Or as Christophe Pedroletti, CEO of Karolinska Universitetssjukhuset expressed it so well:

“A long carried and clear vision – to one day cure and relieve what no one else can cure or relieve today. These are big words, but here at CAST, they are not abstract. They take shape in everyday work, in the corridors, in the treatment rooms, in the research labs, and in conversations with families. And we never do this alone – Karolinska University Hospital and Karolinska Institutet are two parts of the same whole. A partnership where care, research and education move in step. Without that close collaboration we would not be standing here today, celebrating half a century of progress.”

Press Start: The Game Hub in Flemingsberg – Finally!

On April 24th, after just two months of hard work, it was finally time for the kick-off for the game cluster Press Start. The initiative is led by Drivhuset, in close collaboration with Flemingsberg Science Foundation and Södertörn University's Innovation Station.

AlzeCure Pharma – a hope in the fight against Alzheimer’s

Neurological diseases and the pain area are struggling with great medical needs, including the lack of broad-spectrum drugs. Those are gaps in the market that AlzeCure Pharma wants to fill, and they are well on their way. They recently received a grant from the European Innovation Council (EIC) to finance a clinical phase 2 study of the drug candidate NeuroRestore ACD856 for Alzheimer’s disease.

Kick-off Cluster Engine Life Science Flemingsberg!

At the end of last year, the Flemingsberg Science Foundation was granted funding from the European Regional Development Fund (ERDF) for the project Cluster Engine Life Science Flemingsberg, which aims to strengthen the growth and establishment of small and medium-sized enterprises (SMEs) within the life science sector in the Stockholm region. Recently, it was time for the official launch – and what a grand launch it was!

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