50 years of life-changing therapies

On November 12 1975, the first allogeneic bone marrow transplantation in Sweden was performed at Huddinge Hospital, here in Flemingsberg. From nuclear catastrophe the foundations of bone marrow transplantation had emerged, and with it, the birth of modern stem cell therapy — the same principles that today underpin cell and gene therapies and CAR-T treatments.

On November 28th the 50 years passed was celebrated – and 50 years of CAST (Cell Therapy and Allogeneic Stem Cell Transplantation). The unit that, under the leadership of Professors Gösta Gahrton and Carl-Gustav Groth, carried out the historic transplantation, and has since tirelessly worked to develop new therapies, and save lives.

In honor of that a scientific symposium was held in Birkeaulan at Karolinska University Hospital. Led by Professors Stephan Mielke and Mattias Carlsten, leading experts from Sweden and abroad gathered to highlight how innovation in cell and gene therapy can be translated from research to patients. Through lectures and panel discussions, both CAST’s mission and development, as well as global perspectives on advanced treatments, where showcased. The program also provided insight into ongoing research and future possibilities.

The symposium and celebration not only highlighted ongoing research and future opportunities, but also showed how CAST’s five decades of innovation have contributed to shaping today’s advanced treatments and a unique research environment here in Flemingsberg. A reflection of the enormous expertise, courage, and forward-looking spirit among the dedicated staff who work every day to change the lives of thousands of patients. Or as Christophe Pedroletti, CEO of Karolinska Universitetssjukhuset expressed it so well:

“A long carried and clear vision – to one day cure and relieve what no one else can cure or relieve today. These are big words, but here at CAST, they are not abstract. They take shape in everyday work, in the corridors, in the treatment rooms, in the research labs, and in conversations with families. And we never do this alone – Karolinska University Hospital and Karolinska Institutet are two parts of the same whole. A partnership where care, research and education move in step. Without that close collaboration we would not be standing here today, celebrating half a century of progress.”

A national resource for tomorrow’s treatments – Karolinska ATMP Center is now inaugurated

With a clear message of hope for the future and a powerful spirit of collaboration, the Karolinska ATMP Center in Flemingsberg was inaugurated at the end of August. The center is a collaboration between Karolinska Institutet and Karolinska University Hospital and will serve as a national resource for the production of advanced therapies (ATMPs), where research, clinical trials, and treatments work seamlessly together to deliver groundbreaking therapies to patients.

Meetings That Shape the Future: Flemingsberg Science at Almedalen

In June this year, the foundation took part in the annual Almedalen Week, the world’s largest democratic meeting place for everyone who wants to join the discussions on current societal issues. This year, we had a special focus on Life Science, an area and cluster that has long been a natural part of Flemingsberg, and which is now growing stronger than ever.

Meet us at NLSDays

In the south of Stockholm you’ll find Flemingsberg, home to a vibrant life science cluster that’s rapidly emerging as an attractive location for life science companies. Here, academia, business and society form a dynamic ecosystem, fueling innovation and growth. And with more companies establishing and collaborations further deepening, the opportunity to expand and invest have never been greater. This year, we are therefore participating in NLSDays in Gothenburg, where we will showcase Flemingsberg's unique strengths and invite more stakeholders to become part of our thriving life science environment. 

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